Kishen Lab deciphers proteomics underlying engineered chitosan nanoparticle guided immune modulation

Kishen contributed to the findings that the immunomodulatory properties of engineered nanoparticles resulted in polarization of macrophages to drive towards a reparative or healing phenotype. This concept is to achieve self-limiting regulated host-tissue healing as a strategy to eradicate biofilm.

Reference: Hussein H, Kishen A. Proteomic profiling reveals engineered chitosan nanoparticles mediated cellular crosstalk and immunomodulation for therapeutic application in apical periodontitis. Bioact Mater. 2021 Oct 9;11:77-89. doi: 10.1016/j.bioactmat.2021.09.032.